Strange Medical And Epidemic Events From History

  • Do you think you know all the strange things on the list?

Have you heard of these strange medicals and epidemic events? May you know of something that isn’t on the list but should be added?

Dancing Plague of Strasbourg — 1518

Hundreds of people reportedly danced uncontrollably for days or weeks. Some accounts say people died from exhaustion, stroke or heart problems. Modern explanations include mass psychogenic illness and, less convincingly, ergot poisoning. 


Laughing Epidemic — Tanganyika, 1962

At a girls’ school, several students began experiencing uncontrollable laughter. The phenomenon spread, eventually affecting hundreds and forcing institutions to close temporarily. Modern interpretations generally place it among episodes of mass sociogenic illness.  Have you heard of this as one of the strange medicals and epidemic events?

Mass Motor Hysteria — Mattoon, Illinois, 1944

Residents reported an unknown attacker supposedly spraying poisonous gas into homes. People experienced nausea, weakness and strange sensations. Despite extensive investigation, no confirmed “gas attacker” was identified.

Salem Witchcraft Crisis — Massachusetts, 1692–1693

Several young people developed unusual fits and accusations of supernatural attacks spread through the community. More than 150 people were accused of witchcraft and 19 were executed. The episode demonstrates how social fear can transform unexplained symptoms into a collective catastrophe.

Kuru — Papua New Guinea

Kuru was a fatal neurological disease associated historically with ritual funerary practices involving human tissue among the Fore people. It produced progressive neurological deterioration and eventually death. Its study contributed significantly to understanding prion diseases. Have you heard of this as one of the strange medicals and epidemic events?

Spanish Toxic Oil Syndrome — 1981

Contaminated cooking oil caused a massive outbreak affecting more than 20,000 people. Victims developed respiratory, neurological and muscular symptoms. The outbreak permanently changed food-safety practices in Spain.

Minamata Disease — Japan

Industrial mercury contamination entered Minamata Bay and accumulated in fish and shellfish. People consuming contaminated seafood developed severe neurological disease, including loss of coordination and sensory impairment.

St. Anthony’s Fire

Ergot-contaminated grain could cause hallucinations, muscle contractions, convulsions and gangrene. Before the medical cause was understood, outbreaks could appear mysterious or supernatural. Have you heard of this as one of the strange medicals and epidemic events?

Encephalitis Lethargica — 1910s–1920s

A mysterious neurological illness affected large numbers of people in Europe and elsewhere. Some patients became extremely sleepy or developed movement disorders. The cause remains uncertain.

Great Plague of Marseille — France, 1720–1722

Plague arrived in Marseille aboard the ship Grand-Saint-Antoine. The epidemic killed tens of thousands in the region. Authorities eventually imposed strict quarantines, walls and cordons to stop the disease spreading farther.

Which of these these strange medicals and epidemic events are new to you? Tell us what you think in the comments!